SISYPHUS
PUBLICATIONS ONLINE
Try
Tyrosine As An Alternative Anti-Depressant
Tyrosine is one of the lesser known amino
acids, although it was identified way back in the nineteenth
century, and indeed is described as one of those which are
non-essential. Neither of these facts implies,
however, that it is in any way unimportant. Tyrosine is one
of the twenty or so separate amino acids found in the mammalian
body; some of which are known as non-essential because they can
be manufactured by the body, and need not therefore be consumed
in the daily diet.
Ten amino acids, however, cannot be synthesised by the body,
and must be obtained from food. Unsurprisingly perhaps, it
is animal protein foods such as meat, fish and dairy produce
which are the richest source, and they are accordingly known as
first class proteins because they contain all of the essential
amino acids.
The significance of both essential and non-essential amino
acids, however, is that they form the proteins which make up the
bulk of the dry tissue of the human body; most
obviously the muscles. But the importance of protein goes
way beyond this. The different proteins in the body also
form the many enzymes which control its essential biochemical
processes, including the secretion of vital hormones.
Tyrosine is formed in the body from the essential amino acid,
phenylalanine, and in addition to its general role in the
formation of proteins, appears to have a number of more specific
functions.
Tyrosine appears to be directly involved in maintaining good
supplies of the neurotransmitter hormones, adrenalin and
noradrenalin, which are amongst the body’s principal means
of combatting stress, and its function within the brain have also
led many nutritional practitioners to regard the amino acid as a
powerful natural anti-depressant.
Some therapists report excellent results from the use of doses
of up to 1,000 mg a day of tyrosine in treating even sufferers
from the profound, clinical, depression characterised by apathy,
inactivity, social withdrawal and even despair. An
alleviation of even such extreme symptoms has been observed
within as little as a week when patients have been treated with
between 600 mg and 2,000 mg a day. The form of tyrosine
known as acetyl L-tyrosine, however, appears to work more
directly on the brain and doses of a few hundred mg per day of
this compound may be sufficient.
In addition to cases of incapacitating clinical depression,
tyrosine has also been found useful as a short term psychological
tonic for times when an individual nay be suffering from
particular stress, leading to reduced energy levels, confused
thought or lowered mood. To this extent, tyrosine is
also regarded by some as similar to an adaptogen, for example
ginseng, in its general tonic effect.
In its effects on brain chemistry, tyrosine has also proved
useful in alleviating conditions as diverse as Attention Deficit
Disorder (ATD) and the symptoms arising from withdrawal from
cocaine addiction.
Tyrosine is also known to simulate the production of growth
hormone and to stimulate the thyroid gland. Supplementation may
therefore be useful in some cases of an underactive thyroid and
the problems that this may cause.
|
In view of all the above, although it is not strictly necessary to obtain tyrosine from the daily diet, it does not follow that you should not seek to obtain as rich a supply as possible. If you’re enjoying normal health, particularly mental and emotional health, you probably don’t need to take supplements. But in view of the many benefits of tyrosine it is well worth ensuring that you take in a good dietary supply. This can only help with the stability of your moods, mental energy and focus. The best foods for this purpose, of course, are the protein foods, whether vegetable or animal; in particular soy products, nuts, seeds, dairy produce, avocados, poultry and fish. But if supplements are required at times of particular stress or increased energy requirement; tyrosine, like other single amino acids, is best taken on an empty stomach to ensure maximum absorption. As with other single amino supplements, however, these should not be taken in this way in the long term as this may risk the creation of nutritional imbalances. Like all other nutrients in the body, tyrosine can only do its work properly if the body is fully nourished in all other respects. When supplementing with tyrosine, however, it appears particularly important to ensure that generous supplies of vitamins B6 and C are present.
Since these vitamins also function
holistically, this is as always best achieved by taking
comprehensive multi-vitamin and multi-mineral
supplements. There appear to be no known problems of tyrosine toxicity at the dosages discussed in this article, but supplements at higher dose require medical supervision because there are contraindications for those suffering from high blood pressure or taking medication for migraine, Parkinson’s disease, or being treated for certain cancers.
Steve Smith
December 2007 More About Amino Acids, Liquid Vitamins And
Minerals
|